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2014 News Archive
Accordia partner, Dr. Ian Crozier, speaks out on his recovery and his experience treating Ebola patients in Sierra Leone

SAN FRANCISCO, CA - December 8, 2014 - New York Times highlights the story of another American doctor who was diagnosed with the Ebola virus in early September but now has made a full recovery. The Doctor, Ian Crozier, had been in Sierra Leone responding to the outbreak as a volunteer with the World Health Organization.

Dr. Ian Crozier has partnered with Accordia Global Health Foundation since 2008 - as an infectious disease clinician, medical education specialist, and operational research lead – in support of the organization's efforts to permanently improve healthcare systems in Africa.

"I have never encountered a physician more dedicated than Ian is," said Warner C. Greene, MD PhD, Executive Chair of Accordia Global Health Foundation, and Director of the Gladstone Institute of Virology and Immunology. "His life as a physician brought him to Africa where he is both providing the best and most compassionate care possible to his patients and building the clinical skills of his African colleagues. His decision to volunteer with the World Health Organization to respond to the Ebola crisis was completely in keeping with his selfless and courageous commitment to improving health in Africa. We at Accordia are indebted to his efforts, and are delighted that he has made a full recovery."

Dr. Alex Coutinho, Executive Director of the Infectious Diseases Institute, Makerere University added "Ian has been a role model and hero to nearly all of our staff at IDI. His intellectual and empathetic approach to patient care is something we all aspire to as physicians, and his commitment to improving the quality of service provision for patients around the world is an inspiration to all who know him."

To share his story and to emphasize the need for continued investment in health system reform, Accordia is pleased that Dr. Crozier will be joining us at a number of events in San Francisco this week.

Please view the article published today in the New York Times for more details.

GrouponSaysThanks to Accordia

Today, Thursday November 13, 2014, Accordia Global Health Foundation will be featured by Groupon Coupons and receive a portion of the day's proceeds.

Groupon has selected Accordia to feature on their Groupon Coupons website. The GrouponSaysThanks campaign prominently features a select nonprofit partner that is making a big impact on issues that their users care about and donates a portion of the day's proceeds to that partner.

Please visit their website to learn more about the campaign, receive free coupons and promotions, and donate to a good cause today!

CIDRZ Receives Grant from the Bill & Melinda Gates Foundation to Identify Ways to Retain HIV-Infected Persons in Care

WASHINGTON, DC, August 28, 2014 - Accordia Global Health Foundation congratulates the Centre for Infectious Disease Research in Zambia (CIDRZ) and CIDRZ CEO, Dr. Charles Holmes, Deputy CEO, Dr. Izukanji Sikazwe, and Dr Elvin Geng of the University of California San Francisco (UCSF) on the receipt of a $4.76 million award from the Bill & Melinda Gates Foundation to support the Better Information for Health in Zambia study.

The purpose of the Better Information for Health in Zambia study is to more accurately measure loss to follow-up, and to determine the factors that lead to as many as 40% of HIV-infected patients to fall out of enrolled antiretroviral (ART) treatment programs in Zambia. More accurate estimates of the outcomes of HIV patients enrolled in care will assist the Zambian government to make informed decisions about HIV care service provision so that health programs and facilities better meet the needs of their HIV-infected patients, keeping them in care and returning them to health.

The ‘Better Info' study is collaboration between CIDRZ, UCSF, and includes multiple Zambian and other co-Investigators from the University of Alabama at Birmingham, and the University of North Carolina, Chapel Hill. Learn More About the Study

Established in Zambia in 2001 as an extension of an U.S. university, CIDRZ became an independent organization in 2011. This grant is one important demonstration that new CIDRZ leadership has effectively managed the transition to local ownership – while enhancing the quality of its programs and the accountability of its management systems.

Accordia is proud to support a network of Sustainable African Health Institutions like CIDRZ (www.cidrz.org). Permanent, locally-owned African organizations, operating at world class standards, in collaboration with individuals and institutions around the world.

PLOS ONE Publishes IDCAP Facility Performance Results

WASHINGTON DC, August 19, 2014 - In a new paper, published today, Professor Marcia Weaver and colleagues report an overview of the findings from the Integrated Infectious Disease Capacity-Building Evaluation (IDCAP).

Accordia Global Health Foundation, with funding from the Bill & Melinda Gates Foundation, launched IDCAP to better equip mid-level practitioners to manage infectious diseases and to advance the global health community's understanding of the cost-effectiveness of innovative training approaches. IDCAP created a state-of-the-art package of training interventions that incorporated three key elements: 1) a focus on mid-level practitioners, 2) integration across infectious diseases, and 3) on-site support.

The impact of training was tested on three levels: individual clinician capacity and practice, facility performance, and patient health outcomes. Professor Weaver's article, entitled Improving Facility Performance in Infectious Disease Care in Uganda: a Mixed Design Study with Pre/Post and Cluster Randomized Trial Components, describes the impact of the IDCAP interventions on 23 facility performance indicators.

IDCAP improved the quality of care in several areas with a combination of infectious disease training, on-site team training and mentoring, and quality improvement interventions. The IDCAP interventions resulted in statistically significant improvements in six facility performance indicators related to emergency triage, assessment and treatment (ETAT), malaria diagnosis and treatment, pneumonia assessment, and enrollment in HIV care. However, the on-site support intervention alone, significantly improved performance in only one of the 23 facility indicators.

Kelly Willis, Accordia's Executive Director and a co-author, explained, "The majority of research in medicine and public health focuses on a single disease and a single outcome, which is often appropriate. This vertical focus however, may sometimes be to the detriment of professional training and processes of care at a clinic. Accordia is proud to be at the forefront of exploring the integration of training and clinical care."

For additional details about IDCAP, please visit our website.

Ambassador Eric Goosby Joins Accordia Global Health Foundation Board of Directors

Ambassador Eric Goosby Joins Accordia Global Health Foundation Board of Directors

Press Release
For Immediate Release

WASHINGTON, DC, May 8, 2014 – Ambassador Eric Goosby, former U.S. Global AIDS Coordinator and current Professor of clinical medicine at the University of California, San Francisco (UCSF), has been elected to the Accordia Global Health Foundation Board of Directors.

"I am delighted to welcome Ambassador Goosby to our board of directors," said Hank McKinnell, Chair of the Board of Directors for Accordia Global Health Foundation. "He brings a valuable perspective having spearheaded a global effort to manage the scaling up of sustainable HIV/AIDS treatment capacity which has impacted millions. Our board is looking forward to benefitting from Ambassador Goosby's vast experience particularly his successful efforts building public private partnership opportunities as we move forward to expand our network of centers of excellence in Africa."

Ambassador Goosby is currently a Professor in Medicine in the Global Health Sciences program, University of California, San Francisco. Since late 2013, he has been leading the UCSF Global Health Sciences, a new center on implementation sciences that examines the practicalities of running public health programs and applies business-world efficiencies to improve them. Goosby also returned to Ward 86, the AIDS unit at the UCSF-affiliated San Francisco General Hospital and Trauma Center where he worked in the early days of the epidemic.

From 2009 to 2013 Goosby served as the United States Global AIDS Coordinator, leading all U.S. Government international HIV/AIDS efforts. In this role, Goosby oversaw implementation of the U.S. President's Emergency Plan for AIDS Relief (PEPFAR), as well as U.S. Government engagement with the Global Fund to Fight AIDS, Tuberculosis and Malaria. He served on the Operations Committee that leads the U.S. Global Health Initiative, alongside the heads of the U.S. Agency for International Development and the Centers for Disease Control and Prevention. PEPFAR is the cornerstone of the Global Health Initiative, which takes a comprehensive approach to strengthen health systems and improve health outcomes in the developing world. In 2012, Goosby also led the Office of Global Health Diplomacy at the U.S. Department of State. Ambassador Goosby's full bio can be found by visiting the Accordia Website.

Dr. Susan Desmond-Hellman, CEO of the Bill & Melinda Gates Foundation, commented, "As a former board member of Accordia myself, I was pleased to hear of my close friend and colleague's recent appointment. I am not surprised that he was drawn to Accordia's vision of a continent-wide network of centers of excellence in health, driving innovation and expanding permanent health capacity throughout the African region. Ambassador Goosby will provide valuable insight and guidance, strengthening Accordia's already impressive leadership." Accordia establishes, supports and sustains African-owned health institutions, enabling locally relevant research, high quality training and education programs, and essential healthcare services to millions. Almost a decade ago, Accordia helped Uganda's Makerere University establish the Infectious Diseases Institute (IDI) at Makerere University, in Uganda. Today, IDI serves as a model for a sustainable, locally-owned, center of excellence - achieving transformative impact in the region by saving lives, strengthening systems, and offering new career paths to the best and brightest of Africa's health workforce.

Encouraged by the success of its flagship center of excellence in Uganda, Accordia has since committed to replicating that effective model elsewhere on the continent. In 2012, Accordia helped colleagues in Nigeria establish the West African Infectious Diseases Institute as a multi-university collaboration, with a mission to improve the quantity and quality of locally led research and promote its use in setting strong health policy and ensuring effective practice and scale. Accordia also works with a network of more than 20 existing health institutions in 13 African countries - facilitating "South–South" dialogue, encouraging mutual support and technical assistance, and providing opportunities for joint programming for greater regional impact.

"It is an honor to be asked to serve as a member of the Board of Accordia Global Health Foundation," noted incoming Accordia Board Member Ambassador Eric Goosby. "The work Accordia does is critical in supporting the development of a cadre of trained health care professionals, capable and dedicated to ending the HIV epidemic in the region. Accordia's ability to support the development of trained doctors, nurses, and nurse providers has been integral in supporting the scale up of HIV services throughout the region."

Accordia Global Health Foundation is a not-for-profit 501(c)(3) global health organization dedicated to solving Africa's pressing health needs by establishing and supporting sustainable African health institutions. Accordia invests in strengthening African health systems to combat locally relevant health concerns including HIV/AIDS, TB, and malaria. Armed with a vision of creating a continent-wide network of centers of excellence expanding permanent local health capacity, in partnership with a network of distinguished experts from the world's leading academic institutions, Accordia provides guidance and develops management processes and systems that help African centers of excellence succeed.

For further information, please visit our website: http://www.accordiafoundation.org

For investor and media inquiries, please contact:
Melanie Pirchner
Phone: (202) 534-1200
E-mail: mpirchner@accordiafoundation.org

Warner C. Greene, MD, PhD elected to the American Academy of Arts and Sciences

On Monday, April 21, 2014, Warner C. Greene, MD, PhD, Executive Chair of Accordia Global Health Foundation and Founding Director of the Gladstone Institute of Virology and Immunology was elected to the celebrated American Academy of Arts and Sciences. Founded, in 1780, the Academy's purpose is "to cultivate every art and science which may tend to advance the interest, honor, dignity, and happiness of a free, independent, and virtuous people."

Dr. Greene is joining a group of exceptional individuals who have been named to the Academy, from its founders who include John Adams, James Bowdoin, Benjamin Franklin, Thomas Jefferson, and George Washington, to a distinguished membership including Martin Luther King, Jr., Charles Darwin, Albert Einstein, Jonas Salk, Nelson Mandela, Winston Churchill, and John F. Kennedy. There are more than 250 Nobel and Pulitzer Prize winners among the current membership of the Academy.

"Accordia congratulates Dr. Greene on this prestigious honor and applauds his many outstanding scientific and philanthropic accomplishments over the past several decades" said David Greeley, Accordia's CEO & President. He added "I am honored and humbled to have Dr. Greene serve as Executive Chair of our Board."

Dr. Greene will be formally inducted to the Academy on Saturday, October 11, 2014 in Cambridge Massachusetts.

Please join us in congratulating Dr. Greene for this impressive milestone which clearly signifies the high regard in which he is held by leaders in the Arts and Sciences throughout the US and beyond.

2013 Summit on Child Wellness Report Now Available

Changing the Way the World Invests in Africa's Children
2013 Summit on Child Wellness Report

 For nearly a decade, Accordia has convened an annual leadership-level summit to explore forward-minded opportunities to improve health in sub-Saharan Africa and the world. This year, we focused on ways to improve child wellness in resource-limited settings through better integrated, multi-sectoral, and preventive approaches to children's care and development.

In October 2013, Accordia, the University of Malawi, and Michigan State University co-hosted the 2013 Summit on Child Wellness in Mangochi, Malawi. Accordia convened local leaders and global experts in pediatric health and surrounding disciplines and challenged them to think differently about new preventative and multi-sectoral approaches to ensuring healthy, productive lives for children born in resource-limited settings around the world.

Participants, including high-level delegates from five Malawian ministries as well as the vice chancellors of Malawi's three largest universities, held robust discussions on how to achieve new levels of multi-sectoral and inter-disciplinary collaboration in academia, policy and practice; strengthen human resources throughout the system; and build stronger research capabilities to evaluate the impact of novel integrated interventions for improved child wellness.

Output and insights from the Summit's deliberations are detailed in the 2013 Summit on Child Wellness Report: Changing the Way the World Invests in Africa's Children, released today. Additionally the report reflects our shared vision for Accordia's proposed Institute for Child Wellness in Africa (ICWA).

Click here to read the 2013 Summit on Child Wellness Report

Dr. Faith Osier Named Winner of Fifth Annual Merle A. Sande Health Leadership Award

April 10, 2014 Accordia Global Health Foundation is pleased to name Dr. Faith Osier as the 2014 recipient of the prestigious Merle A. Sande Health Leadership Award. An external selection committee convened by Accordia chose Dr. Osier to receive the award, from a large pool of highly qualified applicants hailing from 8 African countries.

Faith Osier, MD, PhD, is a pediatrician whose work focuses on the development of effective malaria vaccines, through the identification of targets and mechanisms underlying naturally acquired immunity. She is currently a Clinical Research Fellow and Group Leader at the Kenya Medical Research Institute (KEMRI)– Centre for Geographic Medicine Research.

"Faith is an absolutely outstanding scientist. She has a passionate long-term commitment to help other young researchers achieve their potential and ultimately improve the health of Africans throughout the continent. I can think of no other candidate who better fulfils the spirit and vision of the Merle A. Sande Health Leadership Award," said Dr. Kevin Marsh, Director KEMRI-Wellcome Trust Research Programme, Kenya.

The award – created in 2010 in memory of Dr. Merle Sande, a founder of Accordia and renowned infectious disease specialist – recognizes the efforts of emerging African healthcare leaders who have contributed significant improvements to the health of their home communities and embody Dr. Sande's passion, intellectual drive, and spirit.

"Merle founded Accordia on the vision that the best way to transform health in Africa was from within. Through establishing and supporting sustainable local health institutions, Accordia is working to nurture promising young African physicians and scientists like Faith to empower them to make the transformative impact that is needed to improve health in Africa." said Accordia's Executive Chair Dr. Warner C. Greene. "The group of nominees for the Fifth Annual Merle A. Sande Health Leadership Award were incredibly strong. While Faith prevailed, I was so impressed with the roster of candidates. I am confident these young leaders are going to make an indelible mark on the continent."

Accordia will present the award to Dr. Osier in October 2014, at Makerere University in Kampala, Uganda.

Full Bio...Dr. Faith Osier trained as a clinician at the University of Nairobi in Kenya where she obtained her MBChB in 1996. She followed this immediately with a one year Medical Internship at Coast General Provincial Hospital, in Kenya where she also worked as a Medical Officer in the department of Medicine until March 1998. Thereafter she took up a post as a Medical Officer/Research Officer at KEMRI-Kilifi, working in the Paediatrics Department of Kilifi District Hospital. It was here that she began to develop her career in research, engaging in clinical research studies and actively taking part in institutional academic meetings including weekly journal clubs and seminars. She subsequently specialized in Paediatrics, training both in Kenya and the United Kingdom, becoming a member of the Royal College of Paediatrics and Child Health UK in 2003 and became a Consultant Paediatrician in Kenya in 2009. In 2004 she undertook a Masters in Human Immunity at the University of Liverpool, UK where she graduated with distinction, and was awarded a prize for being the best student of the year in the Department of immunology. She has a PhD from the Open University, UK and currently works as a Clinical Research Fellow and Group Leader at the KEMRI-CGMRC in Kilifi. She currently holds an Intermediate Fellowship in Public Health and Tropical Medicine from the Wellcome Trust, UK and has recently been awarded the prestigious MRC/DfID African Research Leader fellowship to pursue multi-centre cohort studies in malaria immuno-epidemiology. She is actively involved in capacity building for African Scientists and is building up a dynamic research group in Kilifi.

Accordia's Dr. Greene is Interviewed by PBS for his Breakthrough HIV/AIDS Discovery


Accordia Executive Chair is Among Scientists Discovering How Key Immune Cells Die During HIV Infection and Identifying Potential Drug to Block AIDS

 

SAN FRANCISCO, CA—February 7, 2014—A PBS Special report: In search of a cure, scientists look for where HIV hides, highlights Accordia's Executive Chair, Dr. Warner C. Greene for his recent discovery. Special correspondent Spencer Michels reports on the battle against AIDS transition to a different phase: the hunt for a real and complete cure.

Research led by scientists at the Gladstone Institutes that has identified the precise chain of molecular events in the human body that drives the death of most of the immune system's CD4 T cells as an HIV infection leads to AIDS. Further, they have identified an existing anti-inflammatory drug that in laboratory tests blocks the death of these cells—and now are planning a Phase 2 clinical trial to determine if this drug or a similar drug can prevent HIV-infected people from developing AIDS and related conditions.

Two separate journal articles, published simultaneously on December 19, 2013 in Science and Nature, detail the research from the laboratory of Warner C. Greene, MD, PhD, who directs virology and immunology research at Gladstone, an independent biomedical-research nonprofit. Greene is the Executive Chair of Accordia Global Health Foundation. His lab's Science paper reveals how, during an HIV infection, a protein known as IFI16 senses fragments of HIV DNA in abortively infected immune cells. This triggers the activation of the human enzyme caspase-1 and leads to pyroptosis, a fiery and highly inflammatory form of cell death. As revealed in the Nature paper, this repetitive cycle of abortive infection, cell death, inflammation and recruitment of additional CD4 T cells to the infection "hot zone" ultimately destroys the immune system and causes AIDS. The Nature paper further describes laboratory tests in which an existing anti-inflammatory inhibits caspase-1, thereby preventing pyroptosis and breaking the cycle of cell death and inflammation.

Read the journal articles:

Science
Nature

Accordia Applauds Nomination of Dr. Deborah Brix as US Global AIDS Coordinator

WASHINGTON, DC—January 10, 2014—Accordia Global Health Foundation joins many in the global health community in congratulating Dr. Deborah Brix on her nomination to be the new Ambassador at Large and Coordinator of United States Government Activities to Combat HIV/AIDS Globally. The nomination was announced on Jan. 9 for Dr. Brix to succeed Ambassador Eric Goosby, who left the position to return to clinical research and practice.

Accordia has had a long-standing relationship with PEPFAR, working to combat HIV/AIDS in Africa. Please visit the "what we do" section of Accordia's website to learn more about our work.

Additional information about the nomination is available in a press release from the White House.

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