Yuka Manabe is currently the Associate Director of Global Health Research and Innovation within the Johns Hopkins Center for Global Health, an Associate Professor of Medicine, International Health, and Molecular Microbiology and Immunology and a member of the Johns Hopkins University faculty since 1999 and an infectious diseases clinician. She began her faculty career as a basic science researcher studying the molecular and immunopathogenesis of tuberculosis (TB) in animal models. From 2007 until 2012, she was seconded from JHU first as the Associate Medical Laboratory Director of the Makerere University-Johns Hopkins University Clinical Core Lab and then as the Head of Research at the Infectious Diseases Institute (IDI) in Kampala, Uganda. During her tenure, the Research Department built strong research infrastructure (including a translational research lab to build basic science research), research capacity building programs, and scientific and regulatory oversight which has led to increased academic productivity and formal recognition of the IDI as a Research Center of Excellence. Her own research is in health systems strengthening and implementation science particularly in the area of HIV and TB infection and frugal innovation with an emphasis on point-of-care diagnostics.